Exploring how our genes affect health and disease through advanced DNA analysis.
Official title: HIGH THROUGHPUT GENOTYPING AND DNA SEQUENCING FOR STUDYING THE GENETIC CONTRIBUTIONS TO HUMAN HEALTH AND DISEASE - WHOLE GENOME SEQUENCING, 30X COVERAGE FOR NEI (SHEN)
Funded at Johns Hopkins University · NIH-11219956 · Data updated 2026-11-12
This study is looking at how your genes might affect your health by analyzing DNA samples, and if you join, you could help us learn more about the connection between genetics and different health conditions.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Johns Hopkins University NIH-funded |
| Lab location | 1 site (Baltimore, United States) |
| Project start | September 24, 2024 |
| Project end | September 8, 2027 |
| Funding year | 2024 |
| Award (this year) | $2,400 |
| NIH project number | 75N92024D00013-0-759202400008-1 |
| Project ID | NIH-11219956 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals interested in understanding the genetic factors that may affect their health and are willing to provide DNA samples.
✕Less likely to help
Patients with no interest in genetic research or those who do not wish to provide DNA samples may not benefit from this research.
What this research studies
This research focuses on using high throughput genotyping and whole genome sequencing to investigate the genetic factors that contribute to human health and disease. By analyzing DNA samples with 30X coverage, the study aims to uncover genetic variations that may influence various health conditions. Patients may have the opportunity to contribute their genetic information, which could lead to a better understanding of how genetics play a role in their health. The methodology involves collecting DNA samples and performing detailed genetic analyses to identify potential links between genes and health outcomes.
Why it matters
Potential benefit: If successful, this research could lead to personalized medical approaches based on genetic insights, improving health outcomes for patients.
How similar studies have gone: Previous research using high throughput genotyping and whole genome sequencing has shown promise in identifying genetic contributions to various health conditions, indicating a strong potential for success in this approach.
Where this research is happening
-
Johns Hopkins University
Baltimore, United States Active
Related research
Other NIH-funded projects on the same topics.
-
Targeting hidden brain injuries in iTTP to improve long-term brain health
A researcher aims to find out how silent brain injuries in people with immune thrombotic thrombocytopenic purpura (iTTP) happen, how they affect thinking and stroke risk, and how to prevent them.
-
Accelerated flap coverage for severe leg injuries: earlier reconstruction vs standard timing
This study tests whether doing early flap coverage after a severe leg injury lowers infection risk and improves healing for patients with open wounds and bone injury.
-
Placebo-controlled shunting for iNPH: does the surgery help with walking and balance?
A doctor-led trial at Johns Hopkins will test whether a shunt surgery improves walking and balance in older adults with idiopathic normal pressure hydrocephalus.
-
Omalizumab for COPD patients with allergen sensitization and exposure
A multicenter trial will test whether adding omalizumab helps people with COPD who are allergic to common indoor allergens and are exposed to them.
-
Johns Hopkins Total Worker Health Center focusing on mental health
A nationwide center at Johns Hopkins is working to improve mental health and well-being among workers by studying workplace health strategies and translating findings into practical tools.
-
Role of fat droplets in liver fat and inflammatory signals in NAFLD
A study at Johns Hopkins will explore how fat droplets in the liver influence molecules that drive inflammation and progression of non-alcoholic fatty liver disease (NAFLD) in adults.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.