Exploring how organic reactions work using advanced imaging techniques
Official title: Understanding Mechanisms of Organic Reactions and Processes through Imaging
Funded at University of California-Irvine · NIH-10841982 · Data updated 2026-11-12
This study is exploring how certain chemical reactions work to help create new medicines, using a special imaging technique to see details that other methods might miss, and it's particularly looking at ways to make these reactions more efficient and environmentally friendly.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California-Irvine NIH-funded |
| Lab location | 1 site (Irvine, United States) |
| Project start | September 20, 2024 |
| Project end | August 31, 2029 |
| Funding year | 2024 |
| Award (this year) | $519,573 |
| NIH project number | 1R35GM153291-01 |
| Project ID | NIH-10841982 on NIH RePORTER |
Who could benefit from this research
✓Could help
Patients who may benefit from this research are those with diseases that could be treated by new drugs developed through improved organic synthesis methods.
✕Less likely to help
Patients with conditions unrelated to organic chemistry or drug synthesis may not receive direct benefits from this research.
What this research studies
This research investigates the mechanisms behind organic reactions, which are crucial for developing new therapies for diseases. By utilizing fluorescence lifetime imaging microscopy (FLIM), the study aims to provide detailed insights into reaction intermediates and behaviors that traditional methods miss. The focus is on two specific systems: emulsions for sustainable chemistry and the synthesis of organometallic reagents from metal powders. This innovative approach could lead to a better understanding of organic reactions and improve the efficiency of drug synthesis.
Why it matters
Potential benefit: If successful, this research could enhance the development of new therapeutics by improving our understanding of organic reactions.
How similar studies have gone: While this approach using FLIM in synthetic organic chemistry is novel, similar imaging techniques have shown promise in other areas of chemical research.
Where this research is happening
-
University of California-Irvine
Irvine, United States Active
Researchers
- Principal investigator: Blum, Suzanne a. — University of California-Irvine
- Study coordinator: Blum, Suzanne a.
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.