Exploring how organelles communicate in parasitic organisms.
Understanding inter-organellar communication in apicomplexan parasites
This study looks at how tiny parts inside certain parasites, like those that cause malaria and toxoplasmosis, communicate with each other to stay healthy and survive in different environments, which could help us find new ways to treat these diseases.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Georgia NIH-funded |
| Lab location | 1 site (Athens, United States) |
| Project ID | NIH-10933441 on NIH RePORTER |
What this research studies
This research investigates the communication between organelles in apicomplexan parasites, which are responsible for diseases like malaria and toxoplasmosis. By examining specialized structures called membrane contact sites (MCSs), the study aims to understand how these organelles exchange metabolites and maintain cellular function. The research focuses on the unique adaptations of these parasites as they navigate different environments and host cells, which is crucial for their survival and propagation. Insights gained could lead to a better understanding of their biology and potential new treatment strategies.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals affected by malaria or toxoplasmosis, as well as those at risk of these infections.
Not a fit: Patients with non-parasitic infections or conditions unrelated to apicomplexan parasites may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to the development of novel antiparasitic therapies that target the unique metabolic processes of these parasites.
How similar studies have performed: While the study of inter-organellar communication is well-established in model organisms like yeast and mammals, this research is exploring a relatively novel area in apicomplexan parasites.
Where this research is happening
Athens, United States
- University of Georgia — Athens, United States (Active)
Researchers
- Principal investigator: Huet, Diego — University of Georgia
- Study coordinator: Huet, Diego
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.