Exploring how oral diseases affect lung health in cystic fibrosis patients
Understanding Oral Diseases in Cystic Fibrosis to Develop Tailored Preventive Dental Interventions
This study is looking at how oral health affects lung health in young people with cystic fibrosis, and it’s for teens and young adults aged 12 to 30 who want to help us learn if taking care of their teeth can improve their breathing.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Washington NIH-funded |
| Lab location | 1 site (Seattle, United States) |
| Project ID | NIH-11061896 on NIH RePORTER |
What this research studies
This research investigates the connection between oral health and respiratory issues in adolescents and young adults with cystic fibrosis (CF). By enrolling 210 participants aged 12 to 30, the study will assess oral diseases like caries and gingivitis and their potential impact on lung health. Participants will undergo three study visits over two years, during which researchers will collect data on oral health, respiratory outcomes, and relevant biological samples. The goal is to understand how improving oral health could benefit lung function in CF patients.
Who could benefit from this research
Good fit: Ideal candidates for this research are adolescents and young adults aged 12 to 30 who have been diagnosed with cystic fibrosis.
Not a fit: Patients outside the age range of 12 to 30 or those without a diagnosis of cystic fibrosis may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to tailored dental interventions that improve lung health and overall quality of life for cystic fibrosis patients.
How similar studies have performed: While the link between oral health and respiratory conditions has been suggested, this specific investigation into cystic fibrosis is novel and has not been extensively studied before.
Where this research is happening
Seattle, United States
- University of Washington — Seattle, United States (Active)
Researchers
- Principal investigator: Chi, Donald Leslie — University of Washington
- Study coordinator: Chi, Donald Leslie
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.