NIH-funded research R03 grant

Exploring how older adults with lupus can engage in digital physical activity programs

Official title: Physical Activity Behaviors and Readiness for a Digital Health Physical Activity Intervention inOlder Adults with Systemic Lupus Erythematosus

Funded at Hospital for Special Surgery · NIH-10919876 · Data updated 2026-11-12

This study is looking at how active older adults with lupus are and what might help or hinder them from exercising, so we can create a digital program that makes it easier for them to stay active and healthy.

Quick facts

Grant typeR03 grant
Study typeNIH-funded research
Funding institutionHospital for Special Surgery
NIH-funded
Lab location1 site (New York, UNITED STATES)
Project startSeptember 5, 2023
Project endMay 31, 2026
Funding year2024
Award (this year)$179,925
NIH project number5R03AG082927-02
Project IDNIH-10919876 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are older adults aged 50 and above who have been diagnosed with systemic lupus erythematosus.

Less likely to help

Patients who are younger than 50 years old or do not have a diagnosis of systemic lupus erythematosus may not benefit from this research.

What this research studies

This research investigates the physical activity levels and readiness of older adults with systemic lupus erythematosus (SLE) to participate in a digital health intervention aimed at promoting physical activity. The study focuses on understanding the barriers and facilitators that affect their ability to engage in exercise, particularly given their higher risk for cardiovascular diseases. By gathering preliminary data, the researchers aim to adapt an existing 12-week digital program to better meet the specific needs of this population, ensuring it addresses their unique challenges. The ultimate goal is to enhance physical activity behaviors among older adults with SLE through tailored digital solutions.

Why it matters

Potential benefit: If successful, this research could lead to improved physical activity levels and overall health outcomes for older adults with lupus.

How similar studies have gone: Previous research has shown success in using digital health interventions to promote physical activity among older adults, indicating a promising approach for this specific population.

Where this research is happening

  • Hospital for Special Surgery
    New York, United States
    Active

Researchers

  • Principal investigator: Lieber, Sarah Beth — Hospital for Special Surgery
  • Study coordinator: Lieber, Sarah Beth

Related research

Other NIH-funded projects on the same topics.

  • Immunostimulatory short non-coding RNAs and lupus

    A study in people with lupus looks at tiny RNA pieces that may spark inflammation, to understand if they drive disease activity.

    NIH research Thomas Jefferson University · Philadelphia, United States · NIH-11497703

  • Antiviral factors that limit HIV in people with SLE

    Researchers at Howard University are studying how immune factors in people with lupus may help limit HIV infection.

    NIH research Howard University · Washington, United States · NIH-11470887

  • Mechanistic clues about lupus from immune disorders

    This grant looks at why certain immune disorders in people with genetic immune problems lead to lupus-like symptoms, by studying patients and mouse models.

    NIH research Seattle Children's Hospital · Seattle, United States · NIH-11449228

  • Subjective thinking challenges in adults with lupus as they age

    This grant aims to understand how lupus-related cognitive problems affect adults, especially older adults, and tests a real-time method to track daily fluctuations in those symptoms.

    NIH research Hospital for Special Surgery · New York, UNITED STATES · NIH-11442899

  • Mitochondrial targets of antibodies in lupus (SLE)

    A Johns Hopkins-led study will identify which mitochondrial membrane proteins are targeted by autoantibodies in lupus patients to understand how these immune attacks fuel the disease.

    NIH research Johns Hopkins University · Baltimore, United States · NIH-11440181

  • Influenza, Hydroxychloroquine, and the Windows of Self-Peptide Presentation in Lupus

    A doctor-researcher is studying how flu infection and the lupus medication hydroxychloroquine change the way the immune system shows self-parts to trigger or prevent lupus flares in kids.

    NIH research Children's Hosp of Philadelphia · Philadelphia, United States · NIH-11438703

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.