NIH-funded research NIH-funded research

Exploring how nicotinamide riboside affects thinking and sleep in older veterans

Official title: The benefits of nicotinamide riboside upon cognition and sleep in older veterans

Funded at State University of New York at Buffalo · NIH-11126955 · Data updated 2026-11-12

This study is looking at how a supplement called nicotinamide riboside might help improve thinking skills and sleep quality in older veterans, so we can learn more about how to support healthy aging.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionState University of New York at Buffalo
NIH-funded
Lab location1 site (Amherst, United States)
Project startSeptember 1, 2024
Project endAugust 31, 2025
Funding year2024
Award (this year)$249,000
NIH project number4R00AG079117-03
Project IDNIH-11126955 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are veterans aged 65 and older who may be experiencing cognitive decline or sleep disturbances.

Less likely to help

Patients who are younger than 65 or do not have any cognitive or sleep issues may not benefit from this research.

What this research studies

This research investigates the effects of nicotinamide riboside, a compound thought to support healthy aging, on cognitive function and sleep quality in older veterans. The study aims to understand the molecular mechanisms behind sleep disturbances and cognitive decline, utilizing a combination of clinical expertise in geriatrics and behavioral sleep medicine. Participants will be monitored to assess changes in their cognitive abilities and sleep patterns, contributing to a better understanding of how to promote healthy aging.

Why it matters

Potential benefit: If successful, this research could lead to improved cognitive function and sleep quality for older veterans, enhancing their overall quality of life.

How similar studies have gone: Previous research has shown promising results in using similar compounds to improve cognitive function and sleep in older adults, suggesting potential for success in this approach.

Where this research is happening

  • State University of New York at Buffalo
    Amherst, United States
    Active

Researchers

  • Principal investigator: Weiss, Carleara — State University of New York at Buffalo
  • Study coordinator: Weiss, Carleara

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.