Exploring how neurodegenerative diseases spread in the brain
Innovating high-resolution novel imaging approaches to elucidate mechanisms of prion-like spreadingof neurodegenerative disease
This study is looking at how certain proteins linked to diseases like Alzheimer's and Parkinson's spread in the brain, using special imaging tools to see how they affect brain function, with the hope of finding new ways to help manage these conditions.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Stanford University NIH-funded |
| Lab location | 1 site (Stanford, United States) |
| Project ID | NIH-10869936 on NIH RePORTER |
What this research studies
This research investigates the prion-like spreading of proteins associated with neurodegenerative diseases such as Alzheimer's and Parkinson's. By utilizing advanced imaging techniques, the team aims to visualize how these proteins propagate through the brain and affect its function. The interdisciplinary approach combines expertise from engineering and genetics to develop new methods for tracking these disease mechanisms. Understanding these processes could lead to new therapeutic strategies for managing neurodegenerative diseases.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with Alzheimer's disease or Parkinson's disease.
Not a fit: Patients with neurodegenerative diseases not related to prion-like mechanisms may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to breakthroughs in understanding and treating neurodegenerative diseases.
How similar studies have performed: Other research has shown promising results in understanding prion-like mechanisms in rare diseases, but this approach is novel for common neurodegenerative diseases.
Where this research is happening
Stanford, United States
- Stanford University — Stanford, United States (Active)
Researchers
- Principal investigator: Lee, Jin Hyung — Stanford University
- Study coordinator: Lee, Jin Hyung
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.