Exploring how neighborhood factors and genetics influence Alzheimer's disease risk in Hispanic populations
Integration of Socio-Spatial Data for Neighborhoods with Multi-omic profiles to Identify and Mitigate Factors Affecting Risk of ALzheimer's Disease
This study is looking at how the neighborhoods where Hispanic Americans live might affect their risk of developing Alzheimer's disease, using information collected over many years to find out what factors could help protect their brain health.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Texas Rio Grande Valley NIH-funded |
| Lab location | 1 site (Edinburg, United States) |
| Project ID | NIH-11015361 on NIH RePORTER |
What this research studies
This research investigates the relationship between neighborhood characteristics and the risk of Alzheimer's disease (AD) among Hispanic Americans, particularly focusing on the San Antonio Mexican American Family Study cohort. By integrating multi-omic profiles, which include genetic and metabolic markers, the study aims to uncover how both individual and neighborhood factors contribute to cognitive health. The research will analyze data collected over nearly 30 years to identify specific elements that may mitigate or exacerbate the risk of AD. This approach seeks to provide a deeper understanding of the disparities in AD prevalence between Hispanic and Caucasian populations.
Who could benefit from this research
Good fit: Ideal candidates for participation are Hispanic individuals, particularly those from neighborhoods with varying social and physical characteristics.
Not a fit: Patients who are not of Hispanic descent or those who do not reside in the targeted neighborhoods may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to targeted interventions that reduce the risk of Alzheimer's disease in Hispanic communities.
How similar studies have performed: Previous research has shown that neighborhood factors significantly influence cognitive health, indicating that this approach has potential for success.
Where this research is happening
Edinburg, United States
- University of Texas Rio Grande Valley — Edinburg, United States (Active)
Researchers
- Principal investigator: Maestre, Gladys E. — University of Texas Rio Grande Valley
- Study coordinator: Maestre, Gladys E.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.