Exploring how neighborhood factors affect breast cancer outcomes in Black and White women
Neighborhood redlining, economic deprivation, and the breast tumor epigenome: bridging social and molecular epidemiology to address the Black-White breast cancer mortality disparity
This study is looking at how things like unfair housing practices and economic struggles in your neighborhood might affect breast cancer outcomes, especially for certain types of tumors, and it’s for Black and White women who have been diagnosed with breast cancer in the Atlanta area.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Emory University NIH-funded |
| Lab location | 1 site (Atlanta, United States) |
| Project ID | NIH-10688327 on NIH RePORTER |
What this research studies
This research investigates the impact of neighborhood redlining and economic deprivation on breast cancer outcomes, particularly focusing on estrogen receptor-positive tumors. By examining the epigenome of breast tumors, the study aims to uncover how social stressors related to discriminatory housing policies may influence cancer prognosis. The research will recruit Black and White postmenopausal women diagnosed with breast cancer in metro-Atlanta, utilizing data from the Georgia Cancer Registry to analyze their residential and economic histories. This innovative approach seeks to bridge social and molecular epidemiology to better understand and address disparities in breast cancer mortality.
Who could benefit from this research
Good fit: Ideal candidates for this research are postmenopausal Black and White women diagnosed with estrogen receptor-positive breast cancer stages I-III.
Not a fit: Patients with breast cancer who are not postmenopausal or do not have estrogen receptor-positive tumors may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and interventions that reduce breast cancer mortality disparities between Black and White women.
How similar studies have performed: While this specific approach is novel, previous research has shown that social determinants of health can significantly impact cancer outcomes, indicating potential for success.
Where this research is happening
Atlanta, United States
- Emory University — Atlanta, United States (Active)
Researchers
- Principal investigator: Mccullough, Lauren E — Emory University
- Study coordinator: Mccullough, Lauren E
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.