Exploring how neighborhood disadvantage affects Alzheimer's disease and related dementias.
The Neighborhoods Study: Contextual Disadvantage and Alzheimer’s Disease and Related Dementias (ADRD)
This study looks at how living in a tough neighborhood, where things like poverty and low education are common, can affect the risk and progression of Alzheimer's disease and related dementias, helping us find ways to improve health for those at risk.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Wisconsin-Madison NIH-funded |
| Lab location | 1 site (Madison, United States) |
| Project ID | NIH-11056795 on NIH RePORTER |
What this research studies
This research investigates the impact of socioeconomic factors, specifically neighborhood disadvantage, on the risk and progression of Alzheimer's disease and related dementias (ADRD). By analyzing data from various neighborhoods across the U.S., the study aims to understand how factors like poverty, education, and employment influence cognitive health. The researchers have developed a tool called the Area Deprivation Index (ADI) to quantify neighborhood disadvantage and its effects on health outcomes. This research could lead to targeted interventions that address these social determinants of health.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals from racial/ethnic minority groups or those living in socioeconomically disadvantaged neighborhoods who are at risk for Alzheimer's disease and related dementias.
Not a fit: Patients who do not reside in areas identified as disadvantaged or who do not have a risk of Alzheimer's disease or related dementias may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved strategies for preventing and treating Alzheimer's disease and related dementias in disadvantaged populations.
How similar studies have performed: Previous research has shown that addressing social determinants of health can significantly impact health outcomes, suggesting that this approach may yield valuable insights.
Where this research is happening
Madison, United States
- University of Wisconsin-Madison — Madison, United States (Active)
Researchers
- Principal investigator: Kind, Amy J. — University of Wisconsin-Madison
- Study coordinator: Kind, Amy J.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.