Exploring how NAD+ levels are controlled in cells
Understanding the Regulation of NAD+ Homeostasis and Signaling
This study is looking at how our cells manage a key substance called NAD+, which is important for keeping cells healthy and could help us understand diseases better, using yeast as a model to find new ways to support our health and possibly improve treatments for illnesses.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California at Davis NIH-funded |
| Lab location | 1 site (Davis, United States) |
| Project ID | NIH-11054635 on NIH RePORTER |
What this research studies
This research investigates the regulation of NAD+ metabolism, a crucial metabolite involved in various cellular functions and potential therapeutic target for diseases. The study uses the model organism budding yeast to uncover novel factors that influence NAD+ homeostasis and the mechanisms behind these processes. By identifying specific genetic and signaling pathways that regulate NAD+ levels, the research aims to enhance our understanding of cellular health and longevity. The findings could lead to new insights into how NAD+ metabolism affects human diseases.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with conditions related to NAD+ metabolism or age-related diseases.
Not a fit: Patients with conditions unrelated to NAD+ metabolism or those not affected by age-related diseases may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new therapeutic strategies for diseases linked to NAD+ metabolism.
How similar studies have performed: Other research has shown promising results in understanding NAD+ metabolism, indicating that this approach has potential for significant breakthroughs.
Where this research is happening
Davis, United States
- University of California at Davis — Davis, United States (Active)
Researchers
- Principal investigator: Lin, Su-Ju — University of California at Davis
- Study coordinator: Lin, Su-Ju
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.