NIH-funded research R01 grant

Exploring how multisensory training can help recover vision in blind areas after brain injury

Official title: Mechanisms of multisensory rehabilitation in a primate model of hemianopia

Funded at Wake Forest University Health Sciences · NIH-11045046 · Data updated 2026-11-12

This study is exploring how using both sight and sound together can help people with hemianopia, a condition that makes it hard to see on one side, to improve their vision after a stroke or injury.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionWake Forest University Health Sciences
NIH-funded
Lab location1 site (Winston-Salem, United States)
Project startSeptember 30, 2023
Project endMarch 31, 2027
Funding year2025
Award (this year)$539,498
NIH project number5R01EY035409-03
Project IDNIH-11045046 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are individuals who have experienced a stroke or trauma resulting in hemianopia.

Less likely to help

Patients with hemianopia due to causes unrelated to brain injury or those with irreversible visual impairment may not benefit from this research.

What this research studies

This research investigates how combining visual and auditory cues can aid in the rehabilitation of patients suffering from hemianopia, a condition often caused by stroke or trauma that results in blindness in one half of the visual field. Using a primate model, the study aims to assess the effectiveness of a novel sensory training approach that engages brain plasticity to improve visual awareness and functionality. The methodology involves repeated exposure to synchronized visual and auditory stimuli, which has shown promising results in preliminary studies with both animals and humans. The ultimate goal is to better understand the potential for recovery of visual capabilities in affected individuals.

Why it matters

Potential benefit: If successful, this research could lead to new rehabilitation strategies that significantly improve the quality of life for patients with hemianopia.

How similar studies have gone: Previous studies have shown success with similar multisensory rehabilitation approaches in both animal models and a small number of human cases, indicating potential for further exploration.

Where this research is happening

  • Wake Forest University Health Sciences
    Winston-Salem, United States
    Active

Researchers

  • Principal investigator: Stanford, Terrence R — Wake Forest University Health Sciences
  • Study coordinator: Stanford, Terrence R

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About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.