NIH-funded research NIH-funded research

Exploring how multi-omics can improve understanding of cancer biology

Official title: Utilizing Multi-omics to Facilitate Cancer Biology Research

Funded at University of California, San Francisco · NIH-10897091 · Data updated 2026-11-12

This study is looking at how cancer grows in both kids and adults by examining tissue samples and creating models to find new ways to treat it, which could help develop personalized therapies that work better for each person's unique cancer.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionUniversity of California, San Francisco
NIH-funded
Lab location1 site (San Francisco, United States)
Project startAugust 1, 2023
Project endJuly 31, 2028
Funding year2024
Award (this year)$233,657
NIH project number5R50CA274213-02
Project IDNIH-10897091 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research include individuals diagnosed with pediatric or adult solid tumors.

Less likely to help

Patients with non-solid tumors or those not diagnosed with cancer may not receive any benefit from this research.

What this research studies

This research focuses on using advanced computational tools to study cancer progression in both pediatric and adult solid tumors. By analyzing patient tissue samples and developing preclinical models, the project aims to identify potential drug targets and understand mechanisms of drug resistance. The research employs high-throughput analyses and single-cell RNA sequencing technologies to gain insights that could lead to more effective treatments. Patients may benefit from the findings as they could lead to personalized therapies based on their specific cancer biology.

Why it matters

Potential benefit: If successful, this research could lead to more targeted and effective treatments for various types of cancer.

How similar studies have gone: Other research has shown success in using multi-omics approaches to understand cancer biology, indicating that this methodology is promising.

Where this research is happening

  • University of California, San Francisco
    San Francisco, United States
    Active

Researchers

  • Principal investigator: Lee, Alex — University of California, San Francisco
  • Study coordinator: Lee, Alex

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.