Exploring how minor cannabinoids can help manage chronic pain and inflammation

Neuro-immune mechanisms of minor cannabinoids in inflammatory and neuropathic pain

NIH-funded research University of California, San Francisco · NIH-10655599

This study is looking at how certain natural compounds from cannabis, called minor cannabinoids, might help relieve chronic pain and inflammation without making you feel high, so that people with these conditions can find safer and more effective treatment options.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of California, San Francisco NIH-funded
Lab location1 site (San Francisco, United States)
Project IDNIH-10655599 on NIH RePORTER

What this research studies

This research investigates the potential of minor cannabinoids, which are components of cannabis, to alleviate chronic pain and inflammation without the psychoactive effects associated with THC. The study aims to understand the mechanisms by which these cannabinoids work in the body, particularly their anti-inflammatory properties and their ability to improve pain management. By examining the effects of these natural compounds on pain and inflammation, the research seeks to provide new insights into alternative treatments for chronic pain conditions. Patients may benefit from a better understanding of how these cannabinoids can be used safely and effectively.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals suffering from chronic pain conditions who are seeking alternative pain management options.

Not a fit: Patients who do not experience chronic pain or inflammation may not receive any benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to new, non-psychoactive treatments for chronic pain that improve patient quality of life.

How similar studies have performed: Previous research has shown promising results with cannabinoids in pain management, suggesting that this approach may lead to significant advancements in treatment options.

Where this research is happening

San Francisco, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
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Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.