Exploring how microtubule regulators affect the body's response to DNA damage
The novel role of microtubule regulators in the DNA damage response
This study is looking at how certain proteins help our cells fix damage to their DNA, which is important for keeping us healthy, and it hopes to find new ways to improve cancer treatments for patients.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Univ of North Carolina Chapel Hill NIH-funded |
| Lab location | 1 site (Chapel Hill, United States) |
| Project ID | NIH-11012341 on NIH RePORTER |
What this research studies
This research investigates the role of microtubule regulators in the DNA damage response, which is crucial for maintaining cell health and stability. By examining how these regulators interact with DNA damage sites, the study aims to uncover new mechanisms that could influence cancer progression and treatment outcomes. The approach involves identifying specific proteins involved in DNA repair processes and understanding their functions in cellular responses to damage. Patients may benefit from insights gained that could lead to improved cancer therapies.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with cancer or those at high risk for developing cancer due to genetic factors related to DNA damage response.
Not a fit: Patients with conditions unrelated to DNA damage or those not affected by cancer may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective cancer treatments by enhancing our understanding of DNA repair mechanisms.
How similar studies have performed: Other research has shown promising results in understanding DNA damage response mechanisms, suggesting that this approach could yield valuable insights.
Where this research is happening
Chapel Hill, United States
- Univ of North Carolina Chapel Hill — Chapel Hill, United States (Active)
Researchers
- Principal investigator: Peng, Aimin — Univ of North Carolina Chapel Hill
- Study coordinator: Peng, Aimin
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.