Exploring how microbes affect pancreatic cancer and its spread
Official title: Interrogating the Spatial and Functional Relevance of Microbes in Pancreatic Cancer and Metastasis
Funded at University of Tx Md Anderson Can Ctr · NIH-10990419 · Data updated 2026-11-12
This study is looking at how tiny germs in the body might affect the growth of pancreatic cancer and its spread to the liver, helping us understand how they interact with cancer cells and the immune system.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Tx Md Anderson Can Ctr NIH-funded |
| Lab location | 1 site (Houston, United States) |
| Project start | August 1, 2024 |
| Project end | July 31, 2029 |
| Funding year | 2024 |
| Award (this year) | $537,985 |
| NIH project number | 1R01CA282786-01A1 |
| Project ID | NIH-10990419 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are patients diagnosed with pancreatic ductal adenocarcinoma, especially those with metastatic disease.
✕Less likely to help
Patients with non-cancerous conditions or those with other types of cancer unrelated to pancreatic cancer may not benefit from this research.
What this research studies
This research investigates the role of microbes in pancreatic cancer, particularly how they influence tumor growth and metastasis to the liver. By examining the spatial distribution and functionality of these microbes within tumors, the study aims to understand their impact on cancer progression. The researchers will utilize advanced imaging techniques and sequencing methods to analyze microbial presence at both regional and single-cell levels. This approach could reveal critical insights into how microbes interact with cancer cells and the immune system.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for treating pancreatic cancer by targeting microbial influences on tumor behavior.
How similar studies have gone: Previous research has shown promising results in understanding the role of microbes in cancer, suggesting that this approach could yield valuable insights.
Where this research is happening
-
University of Tx Md Anderson Can Ctr
Houston, United States Active
Researchers
- Principal investigator: Mcallister, Florencia — University of Tx Md Anderson Can Ctr
- Study coordinator: Mcallister, Florencia
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.