Exploring how metabolite profiles relate to breast density in premenopausal women

Metabolite Profiles and Mammographic Density in Premenopausal Women

['FUNDING_R01'] · WASHINGTON UNIVERSITY · NIH-10877092

This study is looking at how certain substances in the blood relate to breast density in premenopausal women to better understand breast cancer risk, and it aims to find new ways to help prevent breast cancer in younger women.

Quick facts

Phase['FUNDING_R01']
Study typeNih_funding
SexAll
SponsorWASHINGTON UNIVERSITY (nih funded)
Locations1 site (SAINT LOUIS, UNITED STATES)
Trial IDNIH-10877092 on ClinicalTrials.gov

What this research studies

This research investigates the relationship between metabolite profiles and mammographic breast density in premenopausal women, aiming to understand how these factors contribute to breast cancer risk. By analyzing blood samples and utilizing metabolomics, the study seeks to identify biological markers that could indicate higher risk for breast cancer. The goal is to uncover new pathways and actionable insights that could lead to improved prevention strategies for breast cancer in younger women. Participants may undergo blood tests and mammograms as part of the study.

Who could benefit from this research

Good fit: Ideal candidates for this research are premenopausal women, particularly those with dense breast tissue or a family history of breast cancer.

Not a fit: Patients who are postmenopausal or do not have dense breast tissue may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to new prevention strategies for breast cancer in premenopausal women by identifying key biological markers.

How similar studies have performed: While metabolomics has been used in various cancer research contexts, its application specifically to mammographic breast density is relatively novel and untested.

Where this research is happening

SAINT LOUIS, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.