Exploring how lipid mediators affect brain cell survival in Alzheimer's disease
Identifying lipid mediator pathways involved in neuronal survival and repair in Alzheimer's disease
['FUNDING_OTHER'] · UNIVERSITY OF CALIFORNIA AT DAVIS · NIH-11192543
This study is looking at how certain fats in the brain can help protect and heal nerve cells in people with Alzheimer's disease, with the hope of finding new ways to support brain health and improve memory.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF CALIFORNIA AT DAVIS (nih funded) |
| Locations | 1 site (DAVIS, UNITED STATES) |
| Trial ID | NIH-11192543 on ClinicalTrials.gov |
What this research studies
This research investigates the role of specific lipid mediators in promoting the survival and repair of neurons in individuals with Alzheimer's disease (AD). The study aims to understand how deficits in these lipid mediators, which are trapped in brain cell membranes, contribute to neuronal loss and cognitive decline. By using tracer studies, researchers will track changes in these lipid mediators over time and their relationship to neuronal health and cognitive function. The ultimate goal is to identify potential therapeutic targets that could enhance neuronal repair and survival in AD patients.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals aged 65 and older who are diagnosed with Alzheimer's disease.
Not a fit: Patients under the age of 65 or those without a diagnosis of Alzheimer's disease may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatments that improve neuronal survival and cognitive function in patients with Alzheimer's disease.
How similar studies have performed: Previous research has shown promise in targeting lipid mediators for neuroprotection, suggesting that this approach could yield significant insights and advancements in Alzheimer's treatment.
Where this research is happening
DAVIS, UNITED STATES
- UNIVERSITY OF CALIFORNIA AT DAVIS — DAVIS, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: TAHA, AMEER — UNIVERSITY OF CALIFORNIA AT DAVIS
- Study coordinator: TAHA, AMEER
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.