Exploring how lipid mediators affect brain cell survival in Alzheimer's disease
Official title: Identifying lipid mediator pathways involved in neuronal survival and repair in Alzheimer's disease
Funded at University of California at Davis · NIH-11192543 · Data updated 2026-11-12
This study is looking at how certain fats in the brain can help protect and heal nerve cells in people with Alzheimer's disease, with the hope of finding new ways to support brain health and improve memory.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California at Davis NIH-funded |
| Lab location | 1 site (Davis, United States) |
| Project start | September 30, 2024 |
| Project end | August 31, 2025 |
| Funding year | 2024 |
| Award (this year) | $795,542 |
| NIH project number | 1R56AG083336-01A1 |
| Project ID | NIH-11192543 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals aged 65 and older who are diagnosed with Alzheimer's disease.
✕Less likely to help
Patients under the age of 65 or those without a diagnosis of Alzheimer's disease may not benefit from this research.
What this research studies
This research investigates the role of specific lipid mediators in promoting the survival and repair of neurons in individuals with Alzheimer's disease (AD). The study aims to understand how deficits in these lipid mediators, which are trapped in brain cell membranes, contribute to neuronal loss and cognitive decline. By using tracer studies, researchers will track changes in these lipid mediators over time and their relationship to neuronal health and cognitive function. The ultimate goal is to identify potential therapeutic targets that could enhance neuronal repair and survival in AD patients.
Why it matters
Potential benefit: If successful, this research could lead to new treatments that improve neuronal survival and cognitive function in patients with Alzheimer's disease.
How similar studies have gone: Previous research has shown promise in targeting lipid mediators for neuroprotection, suggesting that this approach could yield significant insights and advancements in Alzheimer's treatment.
Where this research is happening
-
University of California at Davis
Davis, United States Active
Researchers
- Principal investigator: Taha, Ameer — University of California at Davis
- Study coordinator: Taha, Ameer
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.