Exploring how lifestyle choices affect immune responses in breast cancer
Official title: Linking lifestyles with tumor immune profiles to identify strategies for improving breast cancer outcomes
Funded at Roswell Park Cancer Institute Corp · NIH-11046527 · Data updated 2026-11-12
This study is looking at how things like your diet and exercise can affect the immune system in breast tumors, with the goal of finding ways to help breast cancer patients live better and longer.
Quick facts
| Grant type | R03 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Roswell Park Cancer Institute Corp NIH-funded |
| Lab location | 1 site (Buffalo, United States) |
| Project start | March 1, 2024 |
| Project end | February 28, 2026 |
| Funding year | 2025 |
| Award (this year) | $86,750 |
| NIH project number | 5R03CA289559-02 |
| Project ID | NIH-11046527 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are breast cancer patients who are interested in understanding how their lifestyle choices may impact their treatment and prognosis.
✕Less likely to help
Patients with non-breast cancer diagnoses or those who are unable to provide lifestyle information may not benefit from this research.
What this research studies
This research investigates the relationship between lifestyle factors, such as diet and physical activity, and the immune environment of breast tumors. By examining how these factors influence immune cell behavior within the tumor microenvironment, the study aims to identify strategies that could improve outcomes for breast cancer patients. The approach includes analyzing immune cell types and their functions in relation to various lifestyle exposures, with a focus on understanding how these interactions can affect tumor progression and patient survival. Patients may be asked to provide information about their lifestyle habits and participate in assessments related to their immune profiles.
Why it matters
Potential benefit: If successful, this research could lead to personalized lifestyle recommendations that enhance immune responses and improve breast cancer outcomes.
How similar studies have gone: While there is emerging preclinical evidence supporting the link between lifestyle factors and tumor immunity, this specific approach to studying breast cancer outcomes is relatively novel and has not been extensively tested in clinical settings.
Where this research is happening
-
Roswell Park Cancer Institute Corp
Buffalo, United States Active
Researchers
- Principal investigator: Cannioto, Rikki — Roswell Park Cancer Institute Corp
- Study coordinator: Cannioto, Rikki
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.