Exploring how lifestyle choices affect immune responses in breast cancer

Linking lifestyles with tumor immune profiles to identify strategies for improving breast cancer outcomes

NIH-funded research Roswell Park Cancer Institute Corp · NIH-11046527

This study is looking at how things like your diet and exercise can affect the immune system in breast tumors, with the goal of finding ways to help breast cancer patients live better and longer.

Quick facts

Grant typeR03 grant
Study typeNIH-funded research
Funding institutionRoswell Park Cancer Institute Corp NIH-funded
Lab location1 site (Buffalo, United States)
Project IDNIH-11046527 on NIH RePORTER

What this research studies

This research investigates the relationship between lifestyle factors, such as diet and physical activity, and the immune environment of breast tumors. By examining how these factors influence immune cell behavior within the tumor microenvironment, the study aims to identify strategies that could improve outcomes for breast cancer patients. The approach includes analyzing immune cell types and their functions in relation to various lifestyle exposures, with a focus on understanding how these interactions can affect tumor progression and patient survival. Patients may be asked to provide information about their lifestyle habits and participate in assessments related to their immune profiles.

Who could benefit from this research

Good fit: Ideal candidates for this research are breast cancer patients who are interested in understanding how their lifestyle choices may impact their treatment and prognosis.

Not a fit: Patients with non-breast cancer diagnoses or those who are unable to provide lifestyle information may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to personalized lifestyle recommendations that enhance immune responses and improve breast cancer outcomes.

How similar studies have performed: While there is emerging preclinical evidence supporting the link between lifestyle factors and tumor immunity, this specific approach to studying breast cancer outcomes is relatively novel and has not been extensively tested in clinical settings.

Where this research is happening

Buffalo, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions aggressive breast cancer
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.