Exploring how immune cells interact with skin cells during wound healing
Understanding immune-epithelial interactions during wound repair in live mammals
['FUNDING_R01'] · MICHIGAN STATE UNIVERSITY · NIH-10930069
This study is looking at how immune cells in the skin help heal wounds, especially focusing on special cells called Langerhans cells, to find better ways to treat chronic wounds and prevent problems like infections or cancer.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | MICHIGAN STATE UNIVERSITY (nih funded) |
| Locations | 1 site (EAST LANSING, UNITED STATES) |
| Trial ID | NIH-10930069 on ClinicalTrials.gov |
What this research studies
This research investigates the interactions between immune cells and skin cells to understand how wounds heal in live mammals. By focusing on Langerhans cells, which are key immune sentinels in the skin, the research aims to uncover their role in restoring the skin barrier after injury. The study will utilize advanced techniques to observe these interactions in real-time, providing insights that could lead to new treatments for chronic wounds. The ultimate goal is to develop effective therapies that enhance wound repair and prevent complications such as infections or cancer.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals with chronic wounds or skin injuries that are slow to heal.
Not a fit: Patients with acute wounds that heal normally or those without any skin injuries may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to innovative treatments that significantly improve wound healing and reduce the risk of severe complications.
How similar studies have performed: Previous research has shown promise in understanding immune cell interactions in wound healing, suggesting that this approach could yield valuable insights.
Where this research is happening
EAST LANSING, UNITED STATES
- MICHIGAN STATE UNIVERSITY — EAST LANSING, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: PARK, SANGBUM — MICHIGAN STATE UNIVERSITY
- Study coordinator: PARK, SANGBUM
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Cancers