Exploring how immune cells interact with skin cells during wound healing
Official title: Understanding immune-epithelial interactions during wound repair in live mammals
Funded at Michigan State University · NIH-10930069 · Data updated 2026-11-12
This study is looking at how immune cells in the skin help heal wounds, especially focusing on special cells called Langerhans cells, to find better ways to treat chronic wounds and prevent problems like infections or cancer.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Michigan State University NIH-funded |
| Lab location | 1 site (East Lansing, United States) |
| Project start | September 15, 2023 |
| Project end | July 31, 2028 |
| Funding year | 2024 |
| Award (this year) | $490,245 |
| NIH project number | 5R01AR083086-02 |
| Project ID | NIH-10930069 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals with chronic wounds or skin injuries that are slow to heal.
✕Less likely to help
Patients with acute wounds that heal normally or those without any skin injuries may not benefit from this research.
What this research studies
This research investigates the interactions between immune cells and skin cells to understand how wounds heal in live mammals. By focusing on Langerhans cells, which are key immune sentinels in the skin, the research aims to uncover their role in restoring the skin barrier after injury. The study will utilize advanced techniques to observe these interactions in real-time, providing insights that could lead to new treatments for chronic wounds. The ultimate goal is to develop effective therapies that enhance wound repair and prevent complications such as infections or cancer.
Why it matters
Potential benefit: If successful, this research could lead to innovative treatments that significantly improve wound healing and reduce the risk of severe complications.
How similar studies have gone: Previous research has shown promise in understanding immune cell interactions in wound healing, suggesting that this approach could yield valuable insights.
Where this research is happening
-
Michigan State University
East Lansing, United States Active
Researchers
- Principal investigator: Park, Sangbum — Michigan State University
- Study coordinator: Park, Sangbum
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.