Exploring how HIV affects the brain in people with substance abuse issues
CELL - AND CIRCUIT - SPECIFIC EXPLORATION OF HIV NEUROGENOMICS IN CONTEXT OF OPIATE AND COCAINE ABUSE
This study is looking at how HIV affects the brain, especially for people who also have issues with drugs like opiates and cocaine, to better understand how the virus interacts with brain health and function.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Icahn School of Medicine at Mount Sinai NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project ID | NIH-10811715 on NIH RePORTER |
What this research studies
This research investigates the impact of HIV on the brain, particularly in individuals who also struggle with substance use disorders like opiate and cocaine abuse. By examining brain tissues from HIV-infected individuals, the study aims to understand how HIV integrates into the brain's genetic material and how this may affect brain function. The research will utilize advanced genomic techniques to uncover the relationship between HIV latency and brain health, especially in areas of the brain that are crucial for movement and cognition. This approach could provide insights into the complex interactions between HIV and substance use on brain health.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals living with HIV who also have a history of opiate or cocaine abuse.
Not a fit: Patients who are HIV-negative or do not have a history of substance use disorders may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and treatment options for HIV-associated neurocognitive disorders in patients with substance use issues.
How similar studies have performed: Other research has shown promising results in understanding the interactions between HIV and substance use, but this specific approach is relatively novel.
Where this research is happening
New York, United States
- Icahn School of Medicine at Mount Sinai — New York, United States (Active)
Researchers
- Principal investigator: Akbarian, Schahram — Icahn School of Medicine at Mount Sinai
- Study coordinator: Akbarian, Schahram
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.