Exploring how high triglycerides affect triple negative breast cancer growth and spread
Understanding how elevated triglycerides contribute to triple negative breast cancer growth and metastasis
This study is looking at how high triglyceride levels might affect the growth and spread of triple negative breast cancer, with the goal of finding new ways to help women with this type of cancer.
Quick facts
| Grant type | R37 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Icahn School of Medicine at Mount Sinai NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project ID | NIH-10894868 on NIH RePORTER |
What this research studies
This research investigates the relationship between elevated triglyceride levels and the progression of triple negative breast cancer (TNBC). It focuses on understanding how high triglycerides may contribute to faster tumor growth and metastasis using pre-clinical models. By examining the biological mechanisms involved, including gene expression changes and lipid profiles, the study aims to uncover potential new treatment strategies for women with TNBC. The findings could lead to better clinical practices regarding triglyceride management in breast cancer patients.
Who could benefit from this research
Good fit: Ideal candidates for this research are women diagnosed with triple negative breast cancer who also have elevated triglyceride levels.
Not a fit: Patients with other types of breast cancer or those without elevated triglycerides may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatment options and survival rates for women with triple negative breast cancer.
How similar studies have performed: Previous studies have established a link between elevated triglycerides and breast cancer outcomes, suggesting that this research builds on existing knowledge rather than exploring a completely novel approach.
Where this research is happening
New York, United States
- Icahn School of Medicine at Mount Sinai — New York, United States (Active)
Researchers
- Principal investigator: Gallagher, Emily Jane — Icahn School of Medicine at Mount Sinai
- Study coordinator: Gallagher, Emily Jane
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.