Exploring how HAART affects the progression of HPV-related oral cancer
Understanding the Role of HAART in the Progression of HPV-Associated Oral Cancer
['FUNDING_R01'] · PENNSYLVANIA STATE UNIV HERSHEY MED CTR · NIH-11090330
This study is looking at how a specific HIV treatment called HAART affects the development of HPV-related oral cancers, like head and neck cancer, to help improve care for people living with HIV who are at greater risk for these cancers.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | PENNSYLVANIA STATE UNIV HERSHEY MED CTR (nih funded) |
| Locations | 1 site (HERSHEY, UNITED STATES) |
| Trial ID | NIH-11090330 on ClinicalTrials.gov |
What this research studies
This research investigates the relationship between highly active antiretroviral therapy (HAART) and the progression of HPV-associated oral cancers, particularly head and neck squamous cell carcinoma (HNSCC). It aims to understand how HAART influences cancer development and patient outcomes, especially in individuals living with HIV who are at higher risk for these cancers. The study employs an in vitro model to analyze cancer progression and the biological mechanisms involved, focusing on the differences between HPV-positive and HPV-negative patients. By examining these factors, the research seeks to provide insights that could improve treatment strategies for affected patients.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals diagnosed with HPV-associated oral cancers, especially those who are also living with HIV.
Not a fit: Patients who do not have HPV-related oral cancers or are not infected with HIV may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatment protocols and better outcomes for patients with HPV-related oral cancers, particularly those living with HIV.
How similar studies have performed: Previous research has shown promising results in understanding the impact of HAART on cancer progression in HIV-infected individuals, suggesting that this approach could yield valuable insights.
Where this research is happening
HERSHEY, UNITED STATES
- PENNSYLVANIA STATE UNIV HERSHEY MED CTR — HERSHEY, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: MEYERS, CRAIG M — PENNSYLVANIA STATE UNIV HERSHEY MED CTR
- Study coordinator: MEYERS, CRAIG M
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Acquired Immune Deficiency Syndrome Virus, Acquired Immunodeficiency Syndrome Virus, Cancer Burden, cancer progression, cancer risk