Exploring how gut microbes function in their natural environment

Developing Next-Generation Physiology approaches for human gut microbiome research

NIH-funded research Montana State University - Bozeman · NIH-10888264

This study is looking at the tiny microbes in your gut to see how they work together and help keep you healthy, using special techniques to observe them in their natural environment instead of in a lab.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionMontana State University - Bozeman NIH-funded
Lab location1 site (Bozeman, United States)
Project IDNIH-10888264 on NIH RePORTER

What this research studies

This research focuses on understanding the human gut microbiome by using advanced techniques to study individual microbes in their natural habitats. Instead of isolating microbes in a lab setting, the project aims to observe them in situ, allowing for a better understanding of their roles and interactions within the gut ecosystem. By analyzing mucosal biopsy samples from the gastrointestinal tract, researchers will employ innovative methods to investigate the metabolic activities of these microbes under various conditions. This approach could lead to significant insights into how gut health is maintained and how it can be improved.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals undergoing gastrointestinal biopsies or those with gut-related health issues.

Not a fit: Patients without gastrointestinal conditions or those not undergoing biopsy procedures may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to new strategies for enhancing gut health and treating related diseases.

How similar studies have performed: While the approach of studying gut microbes at single-cell resolution is relatively novel, similar techniques have shown promise in other microbial ecology fields.

Where this research is happening

Bozeman, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.