Exploring how gut bacteria process complex carbohydrates
The Discovery of Novel Metabolic Pathways for the Biosynthesis and Degradation of Complex Carbohydrates within the Human Gut Microbiome
This study is looking at how the good bacteria in our gut help break down and use certain types of sugars, especially focusing on a germ called Campylobacter jejuni that can cause stomach issues, to better understand how these processes keep us healthy.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Texas A&m University NIH-funded |
| Lab location | 1 site (College Station, United States) |
| Project ID | NIH-11005698 on NIH RePORTER |
What this research studies
This research investigates the biochemical pathways that gut bacteria use to synthesize and break down complex carbohydrates. By utilizing advanced techniques such as computational biology, bioinformatics, and metabolomics, the study aims to uncover the metabolic potential of the human gut microbiome, which is crucial for maintaining health. The research will specifically focus on understanding the capsular polysaccharides of Campylobacter jejuni, a major cause of gastroenteritis. This comprehensive approach seeks to clarify the roles of various enzymes and pathways that are currently poorly understood.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with gastrointestinal disorders or those interested in gut health.
Not a fit: Patients without any gastrointestinal issues or those not interested in gut microbiome research may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatments for gastrointestinal diseases and better overall gut health.
How similar studies have performed: Other research has shown promise in understanding gut microbiome functions, but this specific approach to elucidating novel metabolic pathways is relatively novel.
Where this research is happening
College Station, United States
- Texas A&m University — College Station, United States (Active)
Researchers
- Principal investigator: Raushel, Frank M. — Texas A&m University
- Study coordinator: Raushel, Frank M.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.