Exploring how gut bacteria may influence benign breast disease

Identifying the role of the gut microbiome in the etiology of benign breast disease

['FUNDING_OTHER'] · RUTGERS BIOMEDICAL AND HEALTH SCIENCES · NIH-11032896

This study is looking at how the bacteria in your gut might be linked to benign breast disease, which can increase the risk of breast cancer, by examining samples from about 1,800 women to see how hormones might influence these bacteria, and it will also take a closer look at 300 women with a specific type of benign breast disease to learn more about this connection.

Quick facts

Phase['FUNDING_OTHER']
Study typeNih_funding
SexAll
SponsorRUTGERS BIOMEDICAL AND HEALTH SCIENCES (nih funded)
Locations1 site (Newark, UNITED STATES)
Trial IDNIH-11032896 on ClinicalTrials.gov

What this research studies

This research investigates the connection between the gut microbiome and benign breast disease (BBD), which is a known risk factor for breast cancer. By analyzing gut bacteria in approximately 1,800 women, the study aims to uncover how hormonal factors may affect microbial composition and its potential role in BBD. The research will also include a focused analysis of 300 women with a specific subtype of BBD to better understand these associations. This could provide insights into the underlying mechanisms linking gut health and breast disease.

Who could benefit from this research

Good fit: Ideal candidates for this research are women diagnosed with benign breast disease, particularly those with hormonal risk factors.

Not a fit: Patients who do not have benign breast disease or those with other unrelated health conditions may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to new strategies for preventing or managing benign breast disease and potentially reducing breast cancer risk.

How similar studies have performed: While the role of the gut microbiome in various health conditions has been explored, this specific investigation into its impact on benign breast disease is novel and has not been systematically studied before.

Where this research is happening

Newark, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.