Exploring how gut bacteria influence the evolution of fruit flies

Defining the microbiota's response to and influence on the evolution of Drosophila melanogaster

NIH-funded research California State University Fullerton · NIH-10515040

This study looks at how the tiny bacteria living in the guts of fruit flies can influence their health and evolution, helping us understand the important relationship between these microbes and the flies over time.

Quick facts

Grant typeR15 grant
Study typeNIH-funded research
Funding institutionCalifornia State University Fullerton NIH-funded
Lab location1 site (Fullerton, United States)
Project IDNIH-10515040 on NIH RePORTER

What this research studies

This research investigates the role of gut microbiota in the evolution of Drosophila melanogaster, commonly known as fruit flies. By examining how these microorganisms affect the health-related traits of the flies, the study aims to uncover the interactions between the microbiota and the host during evolutionary processes. The researchers will use laboratory selection methods to observe changes in both the flies and their associated bacteria over generations, providing insights into how these relationships shape evolutionary outcomes.

Who could benefit from this research

Good fit: Ideal candidates for participation or benefit from this research would include individuals interested in the role of microbiota in health and evolution, particularly those with conditions influenced by gut bacteria.

Not a fit: Patients with no interest in microbiota or evolutionary biology may not find direct benefits from this research.

Why it matters

Potential benefit: If successful, this research could enhance our understanding of how gut bacteria influence health and evolution, potentially leading to improved healthcare strategies.

How similar studies have performed: While the specific approach of linking microbiota to evolution in Drosophila is relatively novel, similar studies have shown promising results in understanding the role of gut bacteria in other species.

Where this research is happening

Fullerton, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.