Exploring how gut bacteria influence heart disease risk
Statistical Methods for Large Scale Microbiome Studies of Cardiovascular Disease Risk
This study is looking at how the bacteria in our bodies might be linked to heart health and conditions like high blood pressure, with the hope of finding new ways to help manage heart disease.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Fred Hutchinson Cancer Center NIH-funded |
| Lab location | 1 site (Seattle, United States) |
| Project ID | NIH-10819154 on NIH RePORTER |
What this research studies
This research investigates the relationship between the microbiome, which consists of bacteria in our bodies, and cardiovascular disease (CVD) risk factors such as high blood pressure. By utilizing advanced sequencing technology, the study aims to identify specific bacterial communities that may contribute to CVD. The researchers will develop new statistical methods to analyze data from large-scale microbiome studies, enhancing our understanding of how these bacteria affect heart health. Ultimately, this work could lead to new therapeutic strategies for managing cardiovascular diseases.
Who could benefit from this research
Good fit: Ideal candidates for this research are adults aged 21 and older who are at risk for cardiovascular diseases, particularly those with high blood pressure.
Not a fit: Patients who do not have any cardiovascular disease risk factors or are under 21 years old may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to innovative treatments that modify gut bacteria to reduce the risk of cardiovascular diseases.
How similar studies have performed: Other research has shown promising results in linking microbiome profiles to cardiovascular health, suggesting that this approach could yield significant insights.
Where this research is happening
Seattle, United States
- Fred Hutchinson Cancer Center — Seattle, United States (Active)
Researchers
- Principal investigator: Wu, Michael Chiao-an — Fred Hutchinson Cancer Center
- Study coordinator: Wu, Michael Chiao-an
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.