Exploring how gut bacteria and fungi interact and affect health
Official title: Investigation of gut microbiota metabolite-mediated transkingdom interactions with fungi
Funded at Weill Medical Coll of Cornell Univ · NIH-11046665 · Data updated 2026-11-12
This study is looking at how the bacteria and fungi in your gut work together and how they affect your immune system and health, with the goal of finding ways to improve gut health and prevent diseases.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Weill Medical Coll of Cornell Univ NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project start | March 1, 2024 |
| Project end | January 31, 2029 |
| Funding year | 2025 |
| Award (this year) | $804,124 |
| NIH project number | 5R01AI178683-02 |
| Project ID | NIH-11046665 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals with gastrointestinal conditions or those interested in gut health.
✕Less likely to help
Patients with no gastrointestinal issues or those not interested in microbiome-related therapies may not benefit from this research.
What this research studies
This research investigates the interactions between gut bacteria and fungi, focusing on how these relationships influence the immune system and overall health. By using advanced genetic techniques, the team aims to manipulate gut bacteria to better understand their effects on fungal populations in the intestines. The study involves high-throughput screening of bacterial metabolites to identify those that impact fungal behavior, which could lead to new insights into gut health and disease prevention.
Why it matters
Potential benefit: If successful, this research could lead to new treatments for gut-related diseases by harnessing the power of gut microbiota interactions.
How similar studies have gone: While the interactions between gut bacteria and fungi are less explored, similar research has shown promising results in understanding microbial interactions and their effects on health.
Where this research is happening
-
Weill Medical Coll of Cornell Univ
New York, United States Active
Researchers
- Principal investigator: Iliev, Iliyan Dimitrov — Weill Medical Coll of Cornell Univ
- Study coordinator: Iliev, Iliyan Dimitrov
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.