Exploring how gut bacteria affect lung health and immunity
The Gut-Lung Axis: Immunometabolism Linking the Gut Microbiome and Lung Imunity
This study is looking at how the bacteria in your gut might affect your lung health, especially how certain substances from your gut can influence lung inflammation and infections, which could help people with respiratory issues understand the link between gut health and breathing problems.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California, San Francisco NIH-funded |
| Lab location | 1 site (San Francisco, United States) |
| Project ID | NIH-10802283 on NIH RePORTER |
What this research studies
This research investigates the connection between the gut microbiome and lung health, particularly how gut-derived substances influence lung immune responses. It focuses on metabolites like short-chain fatty acids and their role in lung inflammation and infections. By analyzing stool and lung tissue, the study aims to understand how these gut products affect lung cells and their response to injuries. Patients may benefit from insights into how gut health can impact respiratory conditions.
Who could benefit from this research
Good fit: Ideal candidates include individuals with asthma, lung infections, or other respiratory conditions linked to gut health.
Not a fit: Patients with no respiratory issues or those not affected by gut microbiome factors may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatments for asthma and other lung diseases by targeting gut health.
How similar studies have performed: Other research has shown promising results in understanding the gut-lung connection, suggesting that this approach could lead to significant advancements.
Where this research is happening
San Francisco, United States
- University of California, San Francisco — San Francisco, United States (Active)
Researchers
- Principal investigator: Prakash Budde, Arun — University of California, San Francisco
- Study coordinator: Prakash Budde, Arun
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.