Exploring how genetics influence suicidal thoughts and behaviors
Harnessing advances in the genetics of suicidality to identify and dissect psychosocial pathways to risk
This study is looking at how our genes might affect suicidal thoughts and behaviors at different ages, helping us understand the links between genetics, depression, and other issues, so we can better support those who are struggling.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Virginia Commonwealth University NIH-funded |
| Lab location | 1 site (Richmond, United States) |
| Project ID | NIH-11001553 on NIH RePORTER |
What this research studies
This research investigates the genetic factors that contribute to suicidal thoughts and behaviors (STB) across different age groups. By utilizing advanced genome-wide association studies and data from Swedish national registries, the project aims to understand how genetic influences on STB vary throughout a person's life and how they relate to behavioral issues like depression and disinhibition. The study seeks to identify specific genes associated with suicidality and to explore the psychosocial pathways that may increase risk. This comprehensive approach combines genetic data with behavioral assessments to provide a clearer picture of the factors leading to STB.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals aged 12 and older who have experienced suicidal thoughts or behaviors, as well as those with a family history of suicidality.
Not a fit: Patients who do not have a history of suicidal thoughts or behaviors, or those outside the age range of 12 and older, may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved identification of individuals at risk for suicidal thoughts and behaviors, allowing for targeted interventions.
How similar studies have performed: Previous research has shown promising results in understanding the genetic underpinnings of suicidality, indicating that this approach has potential for significant insights.
Where this research is happening
Richmond, United States
- Virginia Commonwealth University — Richmond, United States (Active)
Researchers
- Principal investigator: Edwards, Alexis C — Virginia Commonwealth University
- Study coordinator: Edwards, Alexis C
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.