Exploring how genetics and social factors influence cancer risk in diverse populations.

Understand the mechanisms through which genetics, biology, and social determinants affect cancer risk and outcomes in diverse populations, to motivate interventions to reduce cancer inequities

NIH-funded research Johns Hopkins University · NIH-11045951

This study is looking at how genetics, biology, and social factors affect cancer risk and outcomes, especially for Black patients, to find ways to reduce cancer disparities and improve health for communities that need it most.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionJohns Hopkins University NIH-funded
Lab location1 site (Baltimore, United States)
Project IDNIH-11045951 on NIH RePORTER

What this research studies

This research investigates the complex interplay between genetics, biology, and social determinants that contribute to cancer risk and outcomes, particularly in Black patients. By analyzing data from diverse populations, the study aims to uncover the underlying mechanisms that lead to higher rates of aggressive cancers like prostate, breast, and pancreatic cancers. The research will involve creating a biobank and data repository to gather comprehensive information on environmental exposures and lived experiences, which will help identify factors that contribute to cancer disparities. The ultimate goal is to develop interventions that can reduce cancer inequities and improve health outcomes for marginalized communities.

Who could benefit from this research

Good fit: Ideal candidates for this research include Black patients and individuals from diverse populations who are at risk for aggressive forms of cancer.

Not a fit: Patients who do not belong to the targeted demographic groups or those with cancers unrelated to the focus of this research may not benefit.

Why it matters

Potential benefit: If successful, this research could lead to targeted interventions that significantly reduce cancer disparities and improve outcomes for patients in underserved populations.

How similar studies have performed: Previous research has shown promising results in understanding cancer disparities through genetic and social determinants, indicating that this approach has potential for success.

Where this research is happening

Baltimore, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.