Exploring how genetics and social factors influence cancer risk in diverse populations.
Official title: Understand the mechanisms through which genetics, biology, and social determinants affect cancer risk and outcomes in diverse populations, to motivate interventions to reduce cancer inequities
Funded at Johns Hopkins University · NIH-11045951 · Data updated 2026-11-12
This study is looking at how genetics, biology, and social factors affect cancer risk and outcomes, especially for Black patients, to find ways to reduce cancer disparities and improve health for communities that need it most.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Johns Hopkins University NIH-funded |
| Lab location | 1 site (Baltimore, United States) |
| Project start | May 1, 2024 |
| Project end | April 30, 2026 |
| Funding year | 2024 |
| Award (this year) | $281,874 |
| NIH project number | 1OT2CA297504-01 |
| Project ID | NIH-11045951 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include Black patients and individuals from diverse populations who are at risk for aggressive forms of cancer.
✕Less likely to help
Patients who do not belong to the targeted demographic groups or those with cancers unrelated to the focus of this research may not benefit.
What this research studies
This research investigates the complex interplay between genetics, biology, and social determinants that contribute to cancer risk and outcomes, particularly in Black patients. By analyzing data from diverse populations, the study aims to uncover the underlying mechanisms that lead to higher rates of aggressive cancers like prostate, breast, and pancreatic cancers. The research will involve creating a biobank and data repository to gather comprehensive information on environmental exposures and lived experiences, which will help identify factors that contribute to cancer disparities. The ultimate goal is to develop interventions that can reduce cancer inequities and improve health outcomes for marginalized communities.
Why it matters
Potential benefit: If successful, this research could lead to targeted interventions that significantly reduce cancer disparities and improve outcomes for patients in underserved populations.
How similar studies have gone: Previous research has shown promising results in understanding cancer disparities through genetic and social determinants, indicating that this approach has potential for success.
Where this research is happening
-
Johns Hopkins University
Baltimore, United States Active
Researchers
- Principal investigator: Yates, Clayton — Johns Hopkins University
- Study coordinator: Yates, Clayton
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.