Exploring how genetic mutations affect fertility and health in men.
Official title: Investigating the relationship between genome mutagenesis, fertility, and health in fertile and infertile men
Funded at University of Utah · NIH-11082973 · Data updated 2026-11-12
This study is looking at how certain genetic changes might be linked to male infertility and overall health, and it's for men who are interested in understanding how their genes could affect their fertility and risk for health issues like cancer and heart disease.
Quick facts
| Grant type | Fellowship grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Utah NIH-funded |
| Lab location | 1 site (Salt Lake City, United States) |
| Project start | April 5, 2024 |
| Project end | July 4, 2026 |
| Funding year | 2025 |
| Award (this year) | $25,572 |
| NIH project number | 5F31HD115390-02 |
| Project ID | NIH-11082973 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include men experiencing infertility or those with a family history of related health issues.
✕Less likely to help
Patients who are fertile and have no concerns regarding their reproductive health may not benefit from this research.
What this research studies
This research investigates the connection between genetic mutations and male infertility, aiming to understand how these mutations may impact overall health. The study will analyze DNA from both fertile and infertile men to identify patterns of mutation and their potential links to various health issues, including cancer and cardiovascular diseases. By examining the genetic factors involved, the research seeks to uncover the underlying mechanisms that contribute to infertility and associated health risks. Patients may be asked to provide genetic samples and health information to aid in this investigation.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and management of male infertility and its related health risks.
How similar studies have gone: Previous research has shown promising results in understanding the genetic factors associated with infertility, suggesting that this approach could yield valuable insights.
Where this research is happening
-
University of Utah
Salt Lake City, United States Active
Researchers
- Principal investigator: Kunisaki, Jason — University of Utah
- Study coordinator: Kunisaki, Jason
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.