Exploring how genetic mutations affect fertility and health in men.

Investigating the relationship between genome mutagenesis, fertility, and health in fertile and infertile men

NIH-funded research University of Utah · NIH-11082973

This study is looking at how certain genetic changes might be linked to male infertility and overall health, and it's for men who are interested in understanding how their genes could affect their fertility and risk for health issues like cancer and heart disease.

Quick facts

Grant typeFellowship grant
Study typeNIH-funded research
Funding institutionUniversity of Utah NIH-funded
Lab location1 site (Salt Lake City, United States)
Project IDNIH-11082973 on NIH RePORTER

What this research studies

This research investigates the connection between genetic mutations and male infertility, aiming to understand how these mutations may impact overall health. The study will analyze DNA from both fertile and infertile men to identify patterns of mutation and their potential links to various health issues, including cancer and cardiovascular diseases. By examining the genetic factors involved, the research seeks to uncover the underlying mechanisms that contribute to infertility and associated health risks. Patients may be asked to provide genetic samples and health information to aid in this investigation.

Who could benefit from this research

Good fit: Ideal candidates for this research include men experiencing infertility or those with a family history of related health issues.

Not a fit: Patients who are fertile and have no concerns regarding their reproductive health may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved understanding and management of male infertility and its related health risks.

How similar studies have performed: Previous research has shown promising results in understanding the genetic factors associated with infertility, suggesting that this approach could yield valuable insights.

Where this research is happening

Salt Lake City, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.