Exploring how genes influence complex behaviors in dogs and humans.
Official title: Collaborative Research: EDGE CMT: Utilizing adaptive variation in predatory behavior to uncover the relationship between genes and complex behavioral phenotypes
Funded at Univ of Massachusetts Med Sch Worcester · NIH-11174106 · Data updated 2026-11-12
This study looks at how our genes might influence behaviors in both dogs and people, especially when it comes to things like hunting instincts, to help us better understand behavioral conditions and their genetic links.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Univ of Massachusetts Med Sch Worcester NIH-funded |
| Lab location | 1 site (Worcester, United States) |
| Project start | September 23, 2024 |
| Project end | August 31, 2025 |
| Funding year | 2024 |
| Award (this year) | $771,026 |
| NIH project number | 1R56HG013639-01 |
| Project ID | NIH-11174106 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for participation include individuals with a keen interest in behavioral genetics, particularly those with conditions that may have a genetic component.
✕Less likely to help
Patients with purely environmental or non-genetic behavioral issues may not receive direct benefits from this research.
What this research studies
This research investigates the connection between genetic variations and complex behavioral traits, focusing on both canine and human subjects. By examining predatory behaviors and their adaptive variations, the study aims to uncover how genetics can shape behavior. The methodology includes analyzing genetic data and behavioral assessments to identify patterns and correlations. Patients may benefit from insights that could lead to improved understanding of behavioral conditions and their genetic underpinnings.
Why it matters
Potential benefit: If successful, this research could enhance our understanding of the genetic factors influencing behavior, potentially leading to better treatment options for behavioral disorders.
How similar studies have gone: Previous research has shown promising results in linking genetics to behavior, suggesting that this approach may yield valuable insights.
Where this research is happening
-
Univ of Massachusetts Med Sch Worcester
Worcester, United States Active
Researchers
- Principal investigator: Karlsson, Elinor — Univ of Massachusetts Med Sch Worcester
- Study coordinator: Karlsson, Elinor
Related research
Other NIH-funded projects on the same topics.
-
Understanding HIV-1 Env shapes to boost immune attack against infected cells
Aimed at helping people living with HIV, this project explores how specific HIV-1 envelope structures attract or resist immune attack so future therapies could better help the body clear hidden virus.
-
Reprogramming metabolism to power alternative fat-burning modes
A new project will explore how fat cells burn calories in different ways to help combat obesity.
-
Silencing an Extra Chromosome to Help Down Syndrome and Related Conditions
A patient-friendly plan to use a gene-based approach to quiet an extra chromosome in cells and a mouse model to reduce disease-related effects in Down syndrome and other chromosomal imbalance disorders.
-
Gut microbes and brain function in autism
Researchers are exploring how gut bacteria may influence brain signals and behavior in autism, using worm models to uncover possible links that could someday inform human therapies.
-
Chlamydia and gonorrhea interaction: how host interferons influence co-infection
A human-health focused project looks at how the body’s interferon signals during chlamydia infection affect the way gonorrhea behaves, with potential implications for people vulnerable to both infections.
-
Conquering High Blood Pressure in Vietnamese Cities
A program to adapt and test a proven plan for lowering high blood pressure in urban Vietnam using a mobile health platform and integrated care approach.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.