Exploring how genes and lifestyle factors affect heart and metabolic health across different populations
A Multi-Ancestry Study of Gene-Lifestyle Interactions and Multi-Omics in Cardiometabolic Traits
This study is looking at how your genes and lifestyle choices, like what you eat and how much you exercise, work together to affect your heart and metabolic health, helping us find better ways to prevent and treat conditions like high blood pressure and type 2 diabetes.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Washington University NIH-funded |
| Lab location | 1 site (Saint Louis, United States) |
| Project ID | NIH-10836460 on NIH RePORTER |
What this research studies
This research investigates how genetic factors and lifestyle choices interact to influence cardiometabolic health, including conditions like hypertension and type 2 diabetes. By analyzing diverse populations, the study aims to identify genetic markers associated with these traits and understand how lifestyle factors, such as diet and exercise, impact these genetic influences. The research utilizes advanced techniques, including genome-wide interaction studies and multi-omics data, to uncover the complex relationships between genes and environmental factors. This approach is designed to enhance personalized prevention and treatment strategies for cardiometabolic diseases.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals from diverse ancestry backgrounds who are at risk for or currently experiencing cardiometabolic conditions.
Not a fit: Patients who do not have any cardiometabolic risk factors or conditions may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective, tailored interventions for preventing and managing cardiometabolic diseases.
How similar studies have performed: Previous research has shown promising results in understanding gene-lifestyle interactions, but this study aims to expand on these findings in underrepresented populations.
Where this research is happening
Saint Louis, United States
- Washington University — Saint Louis, United States (Active)
Researchers
- Principal investigator: Rao, Dabeeru C — Washington University
- Study coordinator: Rao, Dabeeru C
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.