NIH-funded research Career grant

Exploring how financial wellbeing affects the risk of Alzheimer's disease and related dementias over a person's life.

Official title: Investigating financial wellbeing, biological aging, and risk of Alzheimers disease and related dementias in a life course synthetic cohort

Funded at Columbia University Health Sciences · NIH-10997316 · Data updated 2026-11-12

This study is looking at how money worries throughout life might affect the chances of developing Alzheimer's and related memory issues, especially focusing on early life stress, to find out when financial help could make a real difference in keeping our minds healthy.

More Alzheimer's Disease research and trials

Quick facts

Grant typeCareer grant
Study typeNIH-funded research
Funding institutionColumbia University Health Sciences
NIH-funded
Lab location1 site (New York, United States)
Project startDecember 15, 2023
Project endNovember 30, 2025
Funding year2025
Award (this year)$131,733
NIH project number5K99AG084769-02
Project IDNIH-10997316 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research include individuals from minoritized groups who may experience financial strain and are at risk for cognitive decline.

Less likely to help

Patients who do not have a history of financial stress or are not at risk for Alzheimer's disease or related dementias may not benefit from this research.

What this research studies

This research investigates the relationship between financial wellbeing and the risk of developing Alzheimer's disease and related dementias (ADRD) throughout a person's life. It focuses on how financial stress, particularly in early life, may contribute to cognitive decline and accelerate biological aging. By analyzing data from multiple datasets, the study aims to identify critical periods when financial interventions could be most effective in reducing ADRD risk. The findings could help inform strategies to improve financial wellbeing and cognitive health.

Why it matters

Potential benefit: If successful, this research could lead to targeted interventions that improve financial wellbeing and reduce the risk of Alzheimer's disease and related dementias.

How similar studies have gone: Previous research has indicated a link between financial stress and cognitive decline, but this study aims to provide novel insights using longitudinal data.

Where this research is happening

  • Columbia University Health Sciences
    New York, United States
    Active

Researchers

  • Principal investigator: Kezios, Katrina L — Columbia University Health Sciences
  • Study coordinator: Kezios, Katrina L

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.