Exploring how external stresses affect biofilms made up of multiple species of bacteria.
Developing platforms for studying the impact of external stresses on multispecies biofilms.
This study is looking at how different stresses, like heat and antibiotics, affect groups of bacteria that can cause infections, with the goal of finding better ways to treat these infections and help patients stay healthy.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Duke University NIH-funded |
| Lab location | 1 site (Durham, United States) |
| Project ID | NIH-10874719 on NIH RePORTER |
What this research studies
This research investigates the impact of various external stresses, such as temperature and antibiotics, on multispecies biofilms, which are clusters of bacteria that can cause significant health issues, including hospital-acquired infections. By developing innovative platforms that simulate real-world conditions, the research aims to better understand how these biofilms form and respond to treatments. The approach involves creating mathematical models and experimental setups that can mimic the conditions under which biofilms thrive, allowing for more effective strategies to combat infections. Patients may benefit from improved infection control measures and treatment options as a result of this work.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals at risk of hospital-acquired infections, particularly those with implanted medical devices or compromised immune systems.
Not a fit: Patients who do not have any risk factors for hospital-acquired infections or biofilm-related complications may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective strategies for preventing and treating infections caused by biofilms, ultimately saving lives and reducing healthcare costs.
How similar studies have performed: Previous research has shown promising results in understanding biofilm behavior and treatment responses, indicating that this approach has potential for significant advancements in infection management.
Where this research is happening
Durham, United States
- Duke University — Durham, United States (Active)
Researchers
- Principal investigator: Jones, Akhenaton-Andrew Dhafir — Duke University
- Study coordinator: Jones, Akhenaton-Andrew Dhafir
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.