Exploring how exercise can improve self-control in people with schizophrenia

An Acute Exercise Intervention to Ameliorate Behavioral and Neurophysiological Indices of Inhibitory Control Deficits in Schizophrenia: A Mobile Brain/Body Imaging (MoBI) Study

NIH-funded research University of Rochester · NIH-11075459

This study is looking at how a short walk can help people with schizophrenia feel better and think more clearly, by checking how their brain and body respond during and after the exercise.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionUniversity of Rochester NIH-funded
Lab location1 site (Rochester, United States)
Project IDNIH-11075459 on NIH RePORTER

What this research studies

This research investigates the effects of a single acute walking intervention on individuals with schizophrenia spectrum disorders (SSDs). Using advanced Mobile Brain/Body Imaging (MoBI) technologies, the study aims to assess changes in behavioral and neurophysiological measures of inhibitory control during and after physical activity. The goal is to determine if exercise can enhance cognitive control and reduce psychosis symptoms, providing insights into the neural mechanisms involved. Participants will engage in tasks while their brain activity is monitored to understand the relationship between exercise and cognitive function.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals aged 21 and older diagnosed with schizophrenia spectrum disorders.

Not a fit: Patients who do not have schizophrenia spectrum disorders or are under 21 years old may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to new therapeutic strategies that utilize exercise to improve cognitive control and reduce symptoms in individuals with schizophrenia.

How similar studies have performed: Previous research has indicated that physical activity can positively impact symptoms of schizophrenia, suggesting potential for success in this novel approach.

Where this research is happening

Rochester, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.