Exploring how exercise can improve self-control in people with schizophrenia
Official title: An Acute Exercise Intervention to Ameliorate Behavioral and Neurophysiological Indices of Inhibitory Control Deficits in Schizophrenia: A Mobile Brain/Body Imaging (MoBI) Study
Funded at University of Rochester · NIH-11075459 · Data updated 2026-11-12
This study is looking at how a short walk can help people with schizophrenia feel better and think more clearly, by checking how their brain and body respond during and after the exercise.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Rochester NIH-funded |
| Lab location | 1 site (Rochester, United States) |
| Project start | September 1, 2024 |
| Project end | August 31, 2026 |
| Funding year | 2024 |
| Award (this year) | $49,974 |
| NIH project number | 1F99NS139427-01A1 |
| Project ID | NIH-11075459 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals aged 21 and older diagnosed with schizophrenia spectrum disorders.
✕Less likely to help
Patients who do not have schizophrenia spectrum disorders or are under 21 years old may not benefit from this research.
What this research studies
This research investigates the effects of a single acute walking intervention on individuals with schizophrenia spectrum disorders (SSDs). Using advanced Mobile Brain/Body Imaging (MoBI) technologies, the study aims to assess changes in behavioral and neurophysiological measures of inhibitory control during and after physical activity. The goal is to determine if exercise can enhance cognitive control and reduce psychosis symptoms, providing insights into the neural mechanisms involved. Participants will engage in tasks while their brain activity is monitored to understand the relationship between exercise and cognitive function.
Why it matters
Potential benefit: If successful, this research could lead to new therapeutic strategies that utilize exercise to improve cognitive control and reduce symptoms in individuals with schizophrenia.
How similar studies have gone: Previous research has indicated that physical activity can positively impact symptoms of schizophrenia, suggesting potential for success in this novel approach.
Where this research is happening
-
University of Rochester
Rochester, United States Active
Researchers
- Principal investigator: Popov, Victoria Anne — University of Rochester
- Study coordinator: Popov, Victoria Anne
Related research
Other NIH-funded projects on the same topics.
-
Understanding social disconnection in schizophrenia using digital signals and brain data
This grant explores how smartphones, social networks, and brain imaging can reveal why Veterans with schizophrenia have trouble forming and maintaining relationships, with the goal of guiding better treatments.
-
Understanding how autism and schizophrenia risk genes affect brain development
Scientists are testing how mutations in certain autism and schizophrenia risk genes change brain cells and networks, using patient-derived cells and organoids.
-
Digital support to spread team-based schizophrenia care in primary care in India
A project to help frontline health workers in India use digital tools to provide coordinated schizophrenia care in primary care, with plans to inform care in the United States as well.
-
Digital support for shared-care of schizophrenia in primary care in India
A patient-friendly plan to bring evidence-based schizophrenia care to primary care in India using digital tools and trained frontline workers.
-
Digital support to scale Schizophrenia care in primary care in India
A nationwide effort to help primary care teams in India deliver better, more accessible schizophrenia care using digital tools and trained frontline workers.
-
How social isolation affects aging health in schizophrenia
This project explores how being socially isolated may speed up health problems as people with schizophrenia age.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.