Exploring how exercise affects muscle health and metabolism
Skeletal Muscle Molecular Drug Targets for Exercise-induced Cardiometabolic Health
This study is looking at how exercise helps our muscles and heart health by exploring the changes it makes at the genetic level, and it's for anyone interested in how staying active can improve their overall well-being.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Duke University NIH-funded |
| Lab location | 1 site (Durham, United States) |
| Project ID | NIH-10818419 on NIH RePORTER |
What this research studies
This research investigates the molecular mechanisms by which exercise influences skeletal muscle and overall cardiometabolic health. By analyzing data from various exercise programs and inactive controls, the study aims to uncover how exercise induces changes at the genetic and protein levels in muscle tissue. This understanding could lead to personalized exercise recommendations and the development of new therapies for health conditions improved by exercise. Participants will contribute to a biorepository of blood and muscle samples, enhancing the research's depth and applicability.
Who could benefit from this research
Good fit: Ideal candidates include individuals interested in improving their metabolic health through exercise, particularly those with conditions that could benefit from enhanced muscle function.
Not a fit: Patients who are unable to engage in any form of exercise or have severe mobility limitations may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to tailored exercise programs and new treatments for conditions related to metabolism and muscle health.
How similar studies have performed: Previous research has shown promising results in understanding the effects of exercise on muscle health, suggesting that this approach could yield valuable insights.
Where this research is happening
Durham, United States
- Duke University — Durham, United States (Active)
Researchers
- Principal investigator: Kraus, William E — Duke University
- Study coordinator: Kraus, William E
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.