Exploring how estrogen affects heart disease risk in women with and without HIV
Understanding the role of estrogen receptor expression in CVD risk in women with and without HIV
This study is looking at how estrogen affects heart health in women with and without HIV, to help understand why younger women with HIV might be at greater risk for heart disease, and it involves checking their blood vessels and arteries to gather important information.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Emory University NIH-funded |
| Lab location | 1 site (Atlanta, United States) |
| Project ID | NIH-10901832 on NIH RePORTER |
What this research studies
This research investigates the role of estrogen receptor expression in cardiovascular disease (CVD) risk among women living with HIV and those without. The study aims to understand how differences in estrogen activity may contribute to the higher incidence of heart disease in young women with HIV. Participants will undergo assessments of vascular function and carotid artery health, while researchers will analyze estrogen receptor gene expression. The project is supported by experienced mentors and utilizes resources from established research centers focused on women's health and HIV.
Who could benefit from this research
Good fit: Ideal candidates for this research include women living with HIV and women without HIV who are at risk for cardiovascular disease.
Not a fit: Patients who are not women or those who do not have risk factors for cardiovascular disease may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and management of cardiovascular disease risk in women, particularly those living with HIV.
How similar studies have performed: Previous research has indicated that hormonal differences can influence cardiovascular health, suggesting that this approach may yield valuable insights.
Where this research is happening
Atlanta, United States
- Emory University — Atlanta, United States (Active)
Researchers
- Principal investigator: Moran, Caitlin — Emory University
- Study coordinator: Moran, Caitlin
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.