Exploring how epigenetic molecules can help treat gum disease
Potentials of Epigenetic Molecules in Attenuating the Phenotypes of Periodontitis
This study is looking at new ways to help treat gum disease by using special molecules that could help your body heal and improve your oral health.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Tufts University Boston NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project ID | NIH-10868743 on NIH RePORTER |
What this research studies
This research investigates the potential of epigenetic molecules to improve treatments for periodontitis, a common gum disease affecting many adults. The team is exploring innovative therapies that target the underlying causes of the disease, such as inflammation and bone loss, using advanced techniques like gene therapy and synthetic inhibitors. By focusing on specific molecules that regulate gene expression, the research aims to stimulate the body's natural ability to regenerate lost tissue and improve overall oral health.
Who could benefit from this research
Good fit: Ideal candidates for this research are adults over the age of 21 who are experiencing symptoms of periodontitis.
Not a fit: Patients with mild gum disease or those who do not have periodontitis may not receive significant benefits from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective treatments for periodontitis, reducing inflammation and promoting bone regeneration.
How similar studies have performed: Other research has shown promise in using epigenetic approaches for various diseases, suggesting potential success for this novel application in periodontitis.
Where this research is happening
Boston, United States
- Tufts University Boston — Boston, United States (Active)
Researchers
- Principal investigator: Chen, Jake Jinkun — Tufts University Boston
- Study coordinator: Chen, Jake Jinkun
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.