Exploring how environmental cues influence nicotine use and addiction
Official title: Understanding and mitigating exacerbated nicotine use resulting from Pavlovianinteroceptive conditioning
Funded at University of Nebraska Lincoln · NIH-11078280 · Data updated 2026-11-12
This study looks at how things around us and how we feel when using nicotine can make some people more likely to become addicted, especially focusing on differences between men and women, to help understand and reduce nicotine dependence.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Nebraska Lincoln NIH-funded |
| Lab location | 1 site (Lincoln, United States) |
| Project start | July 1, 2023 |
| Project end | April 30, 2028 |
| Funding year | 2025 |
| Award (this year) | $359,776 |
| NIH project number | 5R01DA057208-03 |
| Project ID | NIH-11078280 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals who use nicotine products, including smokers and vapers, particularly those who may experience challenges in quitting.
✕Less likely to help
Patients who do not use nicotine products or have no interest in quitting may not benefit from this research.
What this research studies
This research investigates how environmental factors and internal sensations associated with nicotine use can lead to increased addiction and misuse. It focuses on understanding the conditioning processes that make certain stimuli trigger cravings for nicotine, particularly in different sexes. By examining these associations, the study aims to identify why some individuals become more dependent on nicotine and how this can be mitigated. The research employs a combination of behavioral assessments and conditioning experiments to gather data on nicotine-seeking behavior.
Why it matters
Potential benefit: If successful, this research could lead to more effective strategies for preventing and treating nicotine addiction.
How similar studies have gone: Previous research has shown that conditioning processes significantly influence substance use behaviors, suggesting that this approach could yield valuable insights.
Where this research is happening
-
University of Nebraska Lincoln
Lincoln, United States Active
Researchers
- Principal investigator: Bevins, Rick a — University of Nebraska Lincoln
- Study coordinator: Bevins, Rick a
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.