Exploring how dopamine metabolism affects insomnia treatments in cancer survivors
Dopamine Metabolism and Nonpharmacologic Insomnia Interventions Among Cancer Survivors
This study is looking at how well treatments like therapy and acupuncture help cancer survivors with insomnia, and how their body's chemistry might affect these treatments, so if you're a cancer survivor struggling to sleep, you could help us understand what works best for you!
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Sloan-Kettering Inst Can Research NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project ID | NIH-10654842 on NIH RePORTER |
What this research studies
This research investigates the relationship between dopamine metabolism and the effectiveness of nonpharmacologic interventions, such as cognitive behavioral therapy and acupuncture, for treating insomnia in cancer survivors. By utilizing advanced metabolomics technology, the study aims to understand how genetic factors influence treatment responses. Participants will undergo either cognitive behavioral therapy or acupuncture, and their metabolic health will be assessed to determine the impact of these interventions on sleep quality. The goal is to identify specific metabolic changes associated with improved sleep outcomes.
Who could benefit from this research
Good fit: Ideal candidates for this research are cancer survivors experiencing insomnia who are interested in nonpharmacologic treatment options.
Not a fit: Patients who do not have insomnia or are not cancer survivors may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective insomnia treatments tailored to the metabolic profiles of cancer survivors.
How similar studies have performed: Previous studies have shown that cognitive behavioral therapy and acupuncture can effectively improve insomnia in cancer survivors, indicating a promising foundation for this research.
Where this research is happening
New York, United States
- Sloan-Kettering Inst Can Research — New York, United States (Active)
Researchers
- Principal investigator: Mao, Jun J — Sloan-Kettering Inst Can Research
- Study coordinator: Mao, Jun J
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.