Exploring how diverse experiences can boost positive emotions in people with depression

Mapping links between real-world diversity, positive emotion, and neural dynamics in anhedonia

['FUNDING_R01'] · UNIVERSITY OF MIAMI CORAL GABLES · NIH-11086776

This study is looking at how trying new activities and visiting different places can help boost positive feelings in people dealing with depression and PTSD, and it aims to find ways to improve mental health through these real-life experiences.

Quick facts

Phase['FUNDING_R01']
Study typeNih_funding
SexAll
SponsorUNIVERSITY OF MIAMI CORAL GABLES (nih funded)
Locations1 site (CORAL GABLES, UNITED STATES)
Trial IDNIH-11086776 on ClinicalTrials.gov

What this research studies

This research investigates the relationship between experiencing a variety of real-world activities and the enhancement of positive emotions in individuals suffering from depression and PTSD. It aims to identify how increasing 'experiential diversity'—the variety of places and activities one engages in—can positively influence mental health by strengthening specific brain circuits associated with reward and novelty. The study employs advanced techniques such as mobile tracking and resting state fMRI to understand these connections better. By focusing on real-world interventions, the research seeks to develop effective strategies to improve positive affect in patients.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals diagnosed with depression or PTSD who experience reduced positive affect.

Not a fit: Patients who do not have symptoms of depression or PTSD may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to new therapeutic approaches that enhance positive emotions in individuals with depression, improving their overall mental health and quality of life.

How similar studies have performed: Previous research has shown promising results in enhancing positive affect through experiential diversity, indicating that this approach may be effective.

Where this research is happening

CORAL GABLES, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.