Exploring how diet affects our body's internal clock

Uncovering the Impact of Diet on the Human Circadian Timing System

['FUNDING_R01'] · OREGON HEALTH & SCIENCE UNIVERSITY · NIH-10904648

This study is looking at how what we eat, especially high-fat diets, can affect our body's natural clock that helps keep our daily rhythms in sync, and it's for people who want to understand how their diet might impact their health over time.

Quick facts

Phase['FUNDING_R01']
Study typeNih_funding
SexAll
SponsorOREGON HEALTH & SCIENCE UNIVERSITY (nih funded)
Locations1 site (PORTLAND, UNITED STATES)
Trial IDNIH-10904648 on ClinicalTrials.gov

What this research studies

This research investigates the relationship between dietary choices and the human circadian timing system, which regulates our biological processes in sync with the day-night cycle. It aims to understand how different diets, particularly high-fat diets, may disrupt this synchronization, potentially leading to health issues like cardiovascular disease and cognitive decline. By examining these effects in humans, the study seeks to challenge existing theories about circadian rhythms and their regulation. Participants may be asked to provide dietary information and undergo assessments related to their circadian rhythms.

Who could benefit from this research

Good fit: Ideal candidates include individuals who consume high-fat diets and experience issues related to sleep, cognitive function, or metabolic health.

Not a fit: Patients who maintain a balanced diet and do not experience circadian rhythm disruptions may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to new dietary recommendations that improve health by optimizing circadian function.

How similar studies have performed: While similar studies in animal models have shown promising results, this research aims to explore these effects in humans, making it a novel investigation.

Where this research is happening

PORTLAND, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.