NIH-funded research R03 grant

Exploring how daily memory lapses affect heart and blood vessel health.

Official title: Daily Memory Lapses and Sympathetic-Cardiovascular Dysfunction: Pathways to Prevention of Alzheimer's Disease and Related Dementias (ADRD)

Funded at Clemson University · NIH-10724860 · Data updated 2026-11-12

This study is looking at how everyday memory slips might affect heart health in young, healthy adults, especially when those memory lapses cause stress or sadness, and it aims to understand how these feelings could impact the heart.

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Quick facts

Grant typeR03 grant
Study typeNIH-funded research
Funding institutionClemson University
NIH-funded
Lab location1 site (Clemson, United States)
Project startSeptember 1, 2023
Project endAugust 31, 2025
Funding year2023
Award (this year)$318,574
NIH project number1R03AG083323-01
Project IDNIH-10724860 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are young adults aged 21 and older who experience frequent memory lapses and may have depressive symptoms.

Less likely to help

Patients who do not experience memory lapses or have significant cardiovascular issues may not benefit from this research.

What this research studies

This research investigates the relationship between daily memory lapses and cardiovascular health in young, healthy adults. It focuses on how emotional distress caused by these memory lapses may lead to sympathetic-cardiovascular dysfunction. By using daily diary assessments and lab-based evaluations, the study aims to uncover the physiological pathways linking emotional responses to cardiovascular functioning. The research also considers the role of depressive symptoms in exacerbating these effects.

Why it matters

Potential benefit: If successful, this research could lead to new strategies for preventing Alzheimer's disease and related dementias by addressing emotional distress and cardiovascular health.

How similar studies have gone: Previous research has shown that emotional distress can impact cardiovascular health, suggesting that this approach may yield valuable insights.

Where this research is happening

  • Clemson University
    Clemson, United States
    Active

Researchers

  • Principal investigator: Jang, Heejung — Clemson University
  • Study coordinator: Jang, Heejung

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.