Exploring how COVID-19 affects mental health in people living with HIV

Understanding Pandemic Evolution through Networked Data (UPEND)

['FUNDING_OTHER'] · HENRY M. JACKSON FDN FOR THE ADV MIL/MED · NIH-10690892

This study looks at how COVID-19 has affected the mental health and overall well-being of people living with HIV, and it also checks how well COVID-19 vaccines help with these issues, so we can better support those who are most at risk.

Quick facts

Phase['FUNDING_OTHER']
Study typeNih_funding
SexAll
SponsorHENRY M. JACKSON FDN FOR THE ADV MIL/MED (nih funded)
Locations1 site (BETHESDA, UNITED STATES)
Trial IDNIH-10690892 on ClinicalTrials.gov

What this research studies

This research investigates the impact of COVID-19 on the mental health and clinical outcomes of individuals living with HIV. It aims to understand how the pandemic contributes to neurobehavioral issues and to evaluate the effectiveness of COVID-19 vaccinations in mitigating these effects. By analyzing data from multiple HIV-focused cohort studies across several countries, the research will identify factors influencing vaccine uptake and the mental health of people with HIV during the pandemic. The findings will help improve care strategies for this vulnerable population.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals living with HIV, particularly those experiencing mental health challenges during the COVID-19 pandemic.

Not a fit: Patients who do not have HIV or those who are not affected by mental health issues related to COVID-19 may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved mental health outcomes and better clinical management for people living with HIV during pandemics.

How similar studies have performed: Previous research has shown that understanding the intersection of infectious diseases and mental health can lead to significant improvements in patient care, indicating that this approach has potential for success.

Where this research is happening

BETHESDA, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Conditions: Cognition Disorders, cognitive disease, cognitive disorder, cognitive syndrome

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.