NIH-funded research NIH-funded research

Exploring how COVID-19 affects mental health in people living with HIV

Official title: Understanding Pandemic Evolution through Networked Data (UPEND)

Funded at Henry M. Jackson Fdn for the Adv Mil/med · NIH-10690892 · Data updated 2026-11-12

This study looks at how COVID-19 has affected the mental health and overall well-being of people living with HIV, and it also checks how well COVID-19 vaccines help with these issues, so we can better support those who are most at risk.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionHenry M. Jackson Fdn for the Adv Mil/med
NIH-funded
Lab location1 site (Bethesda, United States)
Project startApril 15, 2023
Project endApril 14, 2026
Funding year2023
Award (this year)$3,822,251
NIH project number1RF1MH133442-01
Project IDNIH-10690892 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are individuals living with HIV, particularly those experiencing mental health challenges during the COVID-19 pandemic.

Less likely to help

Patients who do not have HIV or those who are not affected by mental health issues related to COVID-19 may not benefit from this research.

What this research studies

This research investigates the impact of COVID-19 on the mental health and clinical outcomes of individuals living with HIV. It aims to understand how the pandemic contributes to neurobehavioral issues and to evaluate the effectiveness of COVID-19 vaccinations in mitigating these effects. By analyzing data from multiple HIV-focused cohort studies across several countries, the research will identify factors influencing vaccine uptake and the mental health of people with HIV during the pandemic. The findings will help improve care strategies for this vulnerable population.

Why it matters

Potential benefit: If successful, this research could lead to improved mental health outcomes and better clinical management for people living with HIV during pandemics.

How similar studies have gone: Previous research has shown that understanding the intersection of infectious diseases and mental health can lead to significant improvements in patient care, indicating that this approach has potential for success.

Where this research is happening

  • Henry M. Jackson Fdn for the Adv Mil/med
    Bethesda, United States
    Active

Researchers

  • Principal investigator: Crowell, Trevor Adam — Henry M. Jackson Fdn for the Adv Mil/med
  • Study coordinator: Crowell, Trevor Adam

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.