NIH-funded research R21 grant

Exploring how Cognitive Behavioral Therapy for Insomnia affects sleep and fatigue in breast cancer patients

Official title: The Association Between CBT-I Dose, Sleep Duration, and Fatigue in Breast Cancer Patients

Funded at University of Pennsylvania · NIH-10433647 · Data updated 2026-11-12

This study is looking at how different amounts of Cognitive Behavioral Therapy for Insomnia (CBT-I) can help breast cancer patients sleep better and feel less tired during the day, with the goal of improving their overall well-being.

More Breast Cancer research and trials

Quick facts

Grant typeR21 grant
Study typeNIH-funded research
Funding institutionUniversity of Pennsylvania
NIH-funded
Lab location1 site (Philadelphia, United States)
Project startSeptember 23, 2022
Project endAugust 31, 2025
Funding year2022
Award (this year)$417,828
NIH project number1R21CA270987-01
Project IDNIH-10433647 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are breast cancer patients experiencing insomnia and fatigue related to their diagnosis or treatment.

Less likely to help

Patients who do not have breast cancer or those who do not experience insomnia or fatigue may not benefit from this research.

What this research studies

This research investigates the relationship between the dosage of Cognitive Behavioral Therapy for Insomnia (CBT-I), sleep duration, and fatigue levels in patients undergoing treatment for breast cancer. It aims to understand how varying the number of CBT-I sessions can impact sleep quality and daytime fatigue, which are common issues faced by cancer patients. By focusing on the specific needs of breast cancer patients, the study seeks to provide tailored behavioral interventions that could improve their overall well-being. Participants will engage in therapy sessions designed to enhance their sleep patterns and reduce fatigue.

Why it matters

Potential benefit: If successful, this research could lead to improved sleep and reduced fatigue for breast cancer patients, enhancing their quality of life during and after treatment.

How similar studies have gone: Previous studies have shown that CBT-I can be effective for insomnia, but its application in the context of cancer-related fatigue is still being explored.

Where this research is happening

  • University of Pennsylvania
    Philadelphia, United States
    Active

Researchers

  • Principal investigator: Perlis, Michael Lloyd — University of Pennsylvania
  • Study coordinator: Perlis, Michael Lloyd

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.