Exploring how cocaine affects gut bacteria and brain communication
Investigating microbiota of the gut-brain axis and the impact of cocaine
['FUNDING_OTHER'] · ALABAMA STATE UNIVERSITY · NIH-10915725
This study is looking at how cocaine use affects the bacteria in your gut and how those changes might impact your emotions and stress levels, especially for people who struggle with addiction.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | ALABAMA STATE UNIVERSITY (nih funded) |
| Locations | 1 site (MONTGOMERY, UNITED STATES) |
| Trial ID | NIH-10915725 on ClinicalTrials.gov |
What this research studies
This research investigates the relationship between cocaine use and changes in gut microbiota, particularly focusing on how these changes may influence emotional behavior and the body's stress response. By analyzing microbial signatures in the gut-brain axis, the study aims to uncover potential biomarkers related to cocaine overdose. The research specifically targets the impact of cocaine on gut bacteria and its implications for mental health, especially in populations disproportionately affected by addiction. Participants may undergo evaluations that include microbiota analysis and assessments of emotional and physiological responses.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals with a history of cocaine use or addiction, particularly those from African American communities who are disproportionately affected by these issues.
Not a fit: Patients who do not use cocaine or have no history of substance abuse may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new insights into addiction treatment and prevention strategies by understanding the role of gut bacteria in cocaine-related behaviors.
How similar studies have performed: Previous research has shown promising results regarding the influence of gut microbiota on addiction behaviors, suggesting that this approach may yield valuable insights.
Where this research is happening
MONTGOMERY, UNITED STATES
- ALABAMA STATE UNIVERSITY — MONTGOMERY, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: JAVAN, GULNAZ — ALABAMA STATE UNIVERSITY
- Study coordinator: JAVAN, GULNAZ
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Affective Disorders