Exploring how circular RNAs affect aging
Uncovering the functions of circRNAs in aging
['FUNDING_R01'] · BRANDEIS UNIVERSITY · NIH-11072534
This study is looking at how certain tiny molecules called circular RNAs might help protect our brains as we age and could lead to new ways to tackle age-related diseases.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | BRANDEIS UNIVERSITY (nih funded) |
| Locations | 1 site (WALTHAM, UNITED STATES) |
| Trial ID | NIH-11072534 on ClinicalTrials.gov |
What this research studies
This research investigates the role of circular RNAs (circRNAs) in the aging process, particularly their impact on brain function and age-related diseases. By utilizing advanced biochemical and genetic tools, the study aims to uncover how circRNAs regulate gene expression and influence lifespan. The researchers have identified specific circRNAs that may play a protective role against age-related dysfunction, which could lead to new insights into aging mechanisms and potential therapeutic targets.
Who could benefit from this research
Good fit: Ideal candidates for this research include older adults experiencing cognitive decline or those at risk for age-related neurological diseases.
Not a fit: Patients with acute neurological conditions unrelated to aging may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for preventing or treating age-related neurological disorders.
How similar studies have performed: While the role of circRNAs in aging is a relatively novel area of research, preliminary findings suggest potential for significant breakthroughs in understanding age-related diseases.
Where this research is happening
WALTHAM, UNITED STATES
- BRANDEIS UNIVERSITY — WALTHAM, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: KADENER, SEBASTIAN — BRANDEIS UNIVERSITY
- Study coordinator: KADENER, SEBASTIAN
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: age associated disease, age associated disorder, age dependent disease, age dependent disorder, age related human disease